A great inspiration for today's vaccination efforts: Biographical sketch of Francisco Xavier Balmis (1753-1819).

The management of the coronavirus pandemic required huge worldwide vaccination efforts. In this endeavour, healthcare workers faced the twofold challenge of reaching remote areas, and persuading people to take the vaccine. As it happens, this is nothing new in the history of medicine. Health workers may indeed continue to take inspiration from Francisco Xavier Balmis, a Spanish physician of the 19th century who realised the importance of Jenner's vaccine against smallpox, and led a successful expedition to administer the vaccines in the Spanish colonial possessions of the Western hemisphere and Asia. This article presents a biographical sketch of Balmis, focusing on his expedition.

Bence Jones Island in Shepherd Bay, Nunavut: a little known tribute to the legendary physician and chemist's "thé de voyage"

Henry Bence Jones is among the esteemed physicians of the mid-19th century. Eighteen biographical medical journal articles, published between 1952 and 2021, describe his life and contributions to medicine. Unmentioned, however, is an island in the waters of Shepherd Bay in northern Canada, now Nunavut, designated Bence Jones Island, by the British explorer John Rae in 1854. Rae had sailed from Great Britain to the regions extending north of Hudson's Bay in search of information regarding Sir John Franklin and 133 other officers and men who departed from the Kingdom of Great Britain in two ships in 1845 to search for the Northwest Passage to the Pacific Ocean; they disappeared. In anticipation of Rae's voyage to search for evidence of Franklin's expedition, Bence Jones provided a special preparation of tea that could be drunk cold, if necessary. It was so meaningful to the crew of Rae's ship that it resulted in Rae naming an island near Boothia Isthmus in Shepherd Bay in recognition of this contribution to the contentment of his men under arduous conditions and in acknowledgment of Bence Jones's professional standing, upon which we comment. Rae's report of his voyage in 1855, cited herein, mentioned the island and showed its position on a map of the region. We have located it on a current map of the waterways and landmasses of Nunavut using Google Earth Pro by showing its position at the approximate coordinates of latitude and longitude cited by Rae.

Alexander von Humboldt (1769-1859): early high-altitude explorer and renowned plant naturalist.

Alexander von Humboldt (1769-1859) was one of the most distinguished German scientists of the late 18th and early 19th centuries. His fame came chiefly from his extensive explorations in South America and his eminence as a plant naturalist. He attempted to climb the inactive volcano Chimborazo in Ecuador, which was thought to be the highest mountain in the world at the time, and he reached an altitude of about 5,543 m, which was a record height for humans. During the climb, he had typical symptoms of acute mountain sickness, which he correctly attributed to the low level of oxygen, and he was apparently the first person to make this connection. His ability as a naturalist enabled him to recognize the effect of high altitude on the distribution of plants, and by comparing his observations on Chimborazo with those in the European Alps and elsewhere, he inferred that the deleterious effects of high altitude were universal. During his return trip to Europe, he called on President Thomas Jefferson in Washington, where he was given a warm reception, and discussed conservation issues. He then returned to Paris, where he produced 29 volumes over a period of 31 years describing his travels. Here the effects of high altitude on the distribution of plants compared with animals are briefly reviewed. Following Humboldt's death in 1859, there was extensive coverage of his contributions, but curiously, his fame has diminished over the years, and inexplicably, he now has a lower profile in North America.

Death in the Arctic - the tragic fate of members of the Franklin expedition (1845).

In May 1845 HMS Terror and HMS Erebus left England under the command of Sir John Franklin to find the Northwest Passage linking the north Atlantic and Pacific Oceans. The ships had been specially equipped for arctic conditions with central heating, auxiliary steam engines and reinforced steel bows to cut through the ice, however, despite these modern additions neither the vessels nor any of the 129 crew members would ever return. Recently the wrecks of the ships have been located in the waters around King William Island, Nunavut, Canada. Numerous theories have been advanced to explain the deaths that involve lead poisoning, scurvy and zinc deficiency. It is most likely, however, that the deaths were the result of multiple factors such as starvation, hypothermia, infection and general physical and mental decline. Cannibalism occurred but whether this involved the use of already dead sailors or the culling of the weak for food is not determinable. The essential point is that the crews were trapped in the Arctic, many thousands of miles from their homes and families, with dwindling food supplies and minimal chances of rescue.

The Death Zone: Lessons from History.

This Lessons from History article about the naming of the extreme altitude "Death Zone" explores the historical mountaineering and medical literature relevant to the topic. Swiss alpinist and radiologist Edouard Wyss-Dunant (1897-1983) authored several reports and books about expeditions to arctic regions, deserts, and the Himalaya. Encouraged by the success of a Swiss expedition to the Garhwal Himalaya in 1947, Wyss-Dunant joined his fellow climbers from Geneva on a 1949 expedition to several peaks in the Kanchenjunga region. Wyss-Dunant was then invited to lead the spring 1952 Swiss Everest expedition. Despite this being the first Swiss attempt on Everest and on an untried route, Raymond Lambert and Tenzing Norgay nearly summitted Everest from the Nepal side. Wyss-Dunant earned mountaineering immortality by coining the phrase the Death Zone during the expedition's foray into the upper regions of Everest. Wyss-Dunant went on to become a president of the Swiss Alpine Club and the International Climbing and Mountaineering Federation. His writings and that of others provide an evocative supporting narrative to illustrate some of the problems of living (or dying) at extreme altitude.

[From the circumnavigation of the Vital de Oliveira to the new ration tables: nutrition and health on Brazilian Imperial Navy vessels, 1879-1886]. / Da circum-navegação da Vital de Oliveira às novas tabelas de rações: alimentação e saúde a bordo dos navios da Marinha Imperial Brasileira, 1879-1886.

The corvette Vital de Oliveira was the first Brazilian Navy vessel to circumnavigate the world, from 1879 to 1881. One of the items that concerned its captain, Júlio de Noronha, in his trip report was the food supply, which was further reinforced in the medical report for the expedition written by the head surgeon, Galdino Magalhães. This concern was notable due to the high numbers of sailors who sickened and died during the trip, which according to both reports may have been caused by shortages of certain foods. This article discusses the relationship between food and health in the crew, as well as the relationship between this journey and the implementation of a new ration table that took effect in 1886.

Entre 1879 e 1881 a corveta Vital de Oliveira realizou a primeira viagem de circum-navegação da Marinha Brasileira. Um dos itens que ocuparam as preocupações do comandante do navio, Júlio de Noronha, em seu relatório da viagem foi a alimentação; preocupação reforçada no relatório médico da expedição redigido pelo primeiro-cirurgião Galdino Magalhães. Essa preocupação ganhou destaque devido ao elevado saldo de enfermos e mortos durante a viagem, para o que teria contribuído a carência de determinados gêneros alimentícios, de acordo com ambos os relatórios. O artigo discute a relação entre a alimentação e a saúde das tripulações. Além disso, trata da relação entre a viagem da Vital e a implementação de uma nova tabela de rações efetivada em 1886.

Da circum-navegação da Vital de Oliveira às novas tabelas de rações: alimentação e saúde a bordo dos navios da Marinha Imperial Brasileira, 1879-1886 / From the circumnavigation of the Vital de Oliveira to the new ration tables: nutrition and health on Brazilian Imperial Navy vessels, 1879-1886

Resumo Entre 1879 e 1881 a corveta Vital de Oliveira realizou a primeira viagem de circum-navegação da Marinha Brasileira. Um dos itens que ocuparam as preocupações do comandante do navio, Júlio de Noronha, em seu relatório da viagem foi a alimentação; preocupação reforçada no relatório médico da expedição redigido pelo primeiro-cirurgião Galdino Magalhães. Essa preocupação ganhou destaque devido ao elevado saldo de enfermos e mortos durante a viagem, para o que teria contribuído a carência de determinados gêneros alimentícios, de acordo com ambos os relatórios. O artigo discute a relação entre a alimentação e a saúde das tripulações. Além disso, trata da relação entre a viagem da Vital e a implementação de uma nova tabela de rações efetivada em 1886.

Abstract The corvette Vital de Oliveira was the first Brazilian Navy vessel to circumnavigate the world, from 1879 to 1881. One of the items that concerned its captain, Júlio de Noronha, in his trip report was the food supply, which was further reinforced in the medical report for the expedition written by the head surgeon, Galdino Magalhães. This concern was notable due to the high numbers of sailors who sickened and died during the trip, which according to both reports may have been caused by shortages of certain foods. This article discusses the relationship between food and health in the crew, as well as the relationship between this journey and the implementation of a new ration table that took effect in 1886.

Cook's Endeavour, ship of discovery or ship of distemper: an assessment after 250 years.

The 250-year anniversary of Cook's landfall at Botany Bay on 28 April 1770, approximately half way through a global circumnavigation, was an extraordinary maritime undertaking. An enterprise of astronomy, cartography, cultural-botanical documentation and revelation achieved without a death from infectious disease and only 10 mild cases of scurvy in a ship's company of 95 men. The subsequent homeward journey was far less endurable, marked by shipwreck, unforeseen prolonged delays and fatal epidemics of flux and malaria. Mild scurvy within a handful of souls in a crew experimenting with several putative antiscorbutics, yet at voyage's end the precise treatment of scurvy remained enigmatic.

Navegación e historia de la ciencia: La vida a bordo: los hombres de la mar en el siglo XVI / Navigation and history of science: life on board: men of the sea in the 16th Century

El objetivo del presente trabajo fue sintetizar los aspectos básicos de la vida a bordo de los marineros españoles del siglo XVI. Dado el tiempo que pasaban navegando, el barco era la verdadera residencia del marinero, residencia mejor o peor según el rango de la tripulación. Pero si la vida en el barco era dura, muchos de los embarcados estaban en la gloria si se comparaba con sus penurias en tierra, en el barco, al menos, se comía. Horas y horas de trabajo se paliaban con cierto ocio a base de juego, algunas lecturas religiosas y sexo a bordo, que también había. Naufragios, incendios, epidemias, batallas y otros sustos diversos entretenían a los intrépidos marineros, buscavidas de la época. Todo ello en medio de unas lamentables condiciones higiénico-sanitarias, eso sí, no mucho peores que las que se ofrecían en tierra firme

The objective of this study was to synthesize the basic aspects of the Spanish sailors' life on board in the 16th century. Given the time they used to spend sailing, the ship was the sailors' main residence, a better or worse "house" depending on the range of the crew. But if life on board was hard, many of those sailors were in glory when compared with their hardships on land, at least they could eat on the ship. To many hours of work were palliated with some leisure based on games, some religious readings and sex on board, which they also had. Shipwrecks, fires, epidemics, battles and other diverse scares "entertained" the intrepid sailors, a sort of hustlers of the time. All this in the midst of unfortunate hygienic-sanitary conditions, which were not much worse than those offered on the mainland

Expedições científicas e colecionismo: dois exemplos no Brasil-Século XX / Scientific expeditions and collections: two examples in Twentieth Century Brazil

Este trabalho analisará o significado das coleções reunidas em duas séries de expedições científicas realizadas no Brasil, desde o início até meados do século XX. Em primeiro lugar, trata-se de analisar as coleções reunidas durante a chamada Comissão Rondon, na verdade, várias expedições, realizadas entre 1907 e 1915, no início do período republicano no Brasil, período fortemente marcado pelo pensamento positivista. Tinha o objetivo de demarcar estações telegráficas, criando intercomunicação entre os diversos Estados do País e destes com a capital federal e ou o mundo. Em segundo lugar serão consideradas as expedições lideradas pelo antropólogo Luiz de Castro Faria, durante as décadas de 1940 e 1950, no litoral do país, desde o Rio Grande do Sul, até a Bahia. Nesta série, será considerada ainda a conhecida expedição à Serra do Norte, no Mato Grosso, em 1938, cujo chefe foi Claude Lévi-Straus e da qual Castro Faria participou como representante do Museu Nacional e do Conselho de Fiscalização das Expedições Artísticas e Científicas. As coleções reunidas em ambas as séries de expedições destinaram-se ao Museu Nacional do Rio de Janeiro

This work will analyze the meaning of the collections gathered in two series of scientific expeditions carried out in Brazil from the early to the mid-twentieth century. First, it will present the collections gathered during the so-called Rondon Commission, that comprises, in fact, several expeditions held between 1907 and 1915 at the beginning of the republican period in Brazil, a period strongly marked by positivist thinking. The main objective was to construct telegraph lines in order to create intercommunication between the various States of the country and these with the federal capital and or the world. Second, it will approach the expeditions led by the anthropologist Luiz de Castro Faria, during the 1940s and 1950s, along the coast of the country, from Rio Grande do Sul to Bahia. Also, will be considered in this series, the well-known expedition to the Serra do Norte, in Mato Grosso, in 1938, whose head was Claude Lévi-Straus and of which Castro Faria participated as representative of the National Museum and of the Council of Inspection of the Artistic and Scientific Expeditions. The collections assembled in both series of expeditions were destined for the National Museum of Rio de Janeiro

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Archibald Lang McLean (1885-1922) - Explorer, writer and soldier.

Archibald McLean qualified in Sydney in 1910 and in the following year joined Douglas Mawson's Australasian Antarctic Expedition (1911-1914). He took a full part in the expedition and was forced to stay an extra year when Mawson failed to return to the base before the ship left. During this time he edited the expedition newspaper, The Adelie Blizzard. His writing impressed Mawson who invited him to work on the book about the expedition. This necessitated visiting England to liaise with publishers and promote the book. He was in England when the First World War broke out and he was commissioned in the RAMC and sent to France. He was invalided out of the army in 1916 and returned to Australia where he obtained his MD for his research in the Antarctic. Then he joined the Australian Army Medical Corps and returned to France where he won the Military Cross and he also suffered gassing. During the war, he developed TB and was unwell when he returned to Australia.

Framing the transit: expeditionary culture and identities in Lieutenant E.J.W. Noble's caricatures of the 1874 transit of Venus expedition to Honolulu.

Making use of a source previously unknown to historians, this article sheds new light on the British expedition to the Sandwich Islands to observe the 1874 transit of Venus. This source, a series of caricature drawings that follow the expedition from departure to return, gives insight into expeditionary culture and the experience of a previously unremarked member of this astronomical expedition, Evelyn J.W. Noble, a career officer of the Royal Marine Artillery. It also reveals overlapping military, scientific and masculine identities, developed in dialogue with, and often deliberately subverting, more public accounts. The article explores this unique source as a product of naval, imperial and expeditionary cultures; as a contribution to the wide textual and visual culture that surrounded the transit expeditions; and as a series of drawings that united the expedition members through the use of humour and irony, by differentiating the group from others they encountered, and by reflecting or rejecting ideas about the nature of scientific work and personae. The artist represented himself not as a serving officer but as part of a (mostly) united group, dedicated to but humorously self-deprecating about their contribution to the scientific effort.

A brief history of the discovery of tick-borne encephalitis virus in the late 1930s (based on reminiscences of members of the expeditions, their colleagues, and relatives).

Tick-borne encephalitis virus is the etiological agent of a severe human disease transmitted by hard ticks. It occurs in large parts of eastern, central, and western Asia and in Europe with thousands of human cases each year. Here, the discovery of the virus by Soviet scientists in the late 1930s in the Far East is described. The pioneering work involved with this discovery, which resulted in great scientific and epidemiological achievement, was undertaken under the most difficult conditions, and some of the scientists and their technical assistants paid for it with their health and even their lives. This paper briefly outlines the steps on the way that elucidated the basic etiology and eco-epidemiology of the disease, and does not omit that, as one result of the expeditions and the political situation in the former Soviet Union at that time, some scientists were sent to prison.

"Plants that Remind Me of Home": Collecting, Plant Geography, and a Forgotten Expedition in the Darwinian Revolution.

In 1859, Harvard botanist Asa Gray (1810-1888) published an essay of what he called "the abstract of Japan botany." In it, he applied Charles Darwin's evolutionary theory to explain why strong similarities could be found between the flora of Japan and that of eastern North America, which provoked his famous debate with Louis Agassiz (1807-1873) and initiated Gray's efforts to secure a place for Darwinian biology in the American sciences. Notably, although the Gray-Agassiz debate has become one of the most thoroughly studied scientific debates, historians of science remain unable to answer one critical question: How was Gray able to acquire specimens from Japan? Making use of previously unknown archival materials, this article scrutinizes the institutional, instrumental, financial, and military settings that enabled Gray's collector, Charles Wright (1811-1885), to travel to Japan, as well as examine Wright's collecting practices in Japan. I argue that it is necessary to examine Gray's diagnosis of Japan's flora and the subsequent debate about it from the viewpoint of field sciences. The field-centered approach not only unveils an array of historical significances that have been overshadowed by the analytical framework of the Darwinian revolution and the reception of Darwinism, but also places a seemingly domestic incident in a transnational context.